Identification of a novel HOOK3-FGFR1 fusion gene involved in
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A translocation t(2;8)(q12;p11) fuses FGFR1 to a novel partner gene, RANBP2/NUP358, in a myeloproliferative/myelodysplastic neoplasm
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PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport
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Endogenous Hook3 and KIF1C interact specifically. (A) Domain
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CEP110 expression. (A,B) Indicated human poly(A) RNA from Clontech
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PDF) Identification of a Novel HOOK3-FGFR1 Fusion Gene Involved in Activation of The NF-kappaB Pathway
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FGFR mutations identified in human cancer. Mutations present in both
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MYC expression correlates with FGFR1 and chimeric FGFR1 expression
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![Schematic representation of the two partner genes and their fusion](https://www.researchgate.net/publication/13706874/figure/fig6/AS:601790777159686@1520489510102/Schematic-representation-of-the-two-partner-genes-and-their-fusion-products-Vertical.png)
Schematic representation of the two partner genes and their fusion